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[63] Gyuhee Kim, Donghyuk Shin, Sumin Lee, Jaesook Yun, and Sangho Lee (2019). Crystal structure of IlvC, a ketol-acid reductoisomerase, from Streptoccocus pneumoniae. Crystals 9(11):551. https://doi.org/10.3390/cryst9110551. November 1, 2019 (online: October 24, 2019).


[62] Seungsu Han, Ji-young Lee, Yeongmok Lee, Tae-Houn Kim, and Sangho Lee (2019). Comprehensive survey of the VxGΦL motif of PP2Cs from Oryza sativa reveals the critical role of the fourth position in regulation of ABA responsiveness. Plant Mol. Biol. 101(4,5):455-469.  https://doi.org/10.1007/s11103-019-00916-9. November 1, 2019 (online: September 20, 2019).


[61] Myung Ki Min, Eun-Hye Choi, Jin-Ae Kim, In Sun Yoon, Seungsu Han, Yeongmok Lee, Sangho Lee and Beom-Gi Kim (2019). Two clade A phosphatase 2Cs expressed in guard cells physically interact with abscisic acid signaling components to induce stomatal closure in rice. Rice 12:37. https://doi.org/10.1186/s12284-019-0297-7December 1, 2019.


[60] Seungsu Han, Yeongmok Lee, Eun Joo Park, Yongsang Lee, Tae-Houn Kim, Beom-Gi Kim and Sangho Lee (2019). Structural determinants for pyrabactin recognition in ABA receptors in Oryza sativaPlant Mol. Biol. 100(3):319-333. https://doi.org/10.1007/s11103-019-00862-6. June 1, 2019 (online: April 2, 2019).


[59] Dongho Kim, Soobin Park and Sangho Lee (2019). Antibody reformatting vector system (AbVec): a platform for converting single-chain variable fragment format to other ones using shared restriction enzyme sites. Biodesign 7(1):12-17.



[58] Seungyeop Lee, Prachetash Ghosh, Hyogyoung Kwon, Sang-Sang Park, Gyu-Lee Kim, Sangh-Yoon Choi, Thao Dang-Hein Tran, Seung Han Seon, Nhat Tu Le, Hamid Iqbal, Sangho Lee, Suhkneung Pyo and Dong-Kwon Rhee (2018). Induction of the pneumococcal vncRS operon by lactoferrin is essential for pneumonia. Virulence 9(1):1562-1575. https://doi.org/10.1080/21505594.2018.1526529.


[57] Doyoun Kim, Jeonghwan Hur, Ji Hoon Han, Sungchul Ha, Donghyuk Shin, Sangho Lee, Soyoung Park, Iroshi Sugiyama and Kyeong Kyu Kim (2018). Sequence preference and structural heterogeneity of BZ junctions. Nucleic Acids Res. 46(19):10504-10513. https://doi.org/10.1093/nar/gky784. November 2, 2018.


[56] Dongho Kim, ShinA Jang, Jihye Oh, Seungsu Han, Soobin Park, Prachetash Ghosh, Dong-Kwon Rhee and Sangho Lee (2018). Molecular characterization of single-chain antibody variable fragments (scFv) specific to Pep27 from Streptococcus pneumoniae. Biochem. Biophys. Res. Commun. 501:718-723.



[55] Donghyuk Shin, Wooju Na, Ji-Hyung Lee, Gyu Hee Kim, Jiseok Baek, Seok Hee Park, Cheol Yong Choi and Sangho Lee (2017). Site-specific monoubiquitination downregulates Rab5 by disrupting effector binding and quanine nucleotide conversion. eLife 6:e29154. https://doi.org/10.7554/eLife.29154.


[54] Hannah Pyo, Cho Yeon Lee, Daehee Kim, Gyuhee Kim, Sangho Lee and Wan Soo Yun (2017). Electrical detection of pneumococcus through nanoparticle decoration method. Sensors 17(9): 2012. https://doi.org/10.3390/s17092012


[53] Seungsu Han, Myung Ki Min, Su-Youn Lee, Chae Woo Lim, Nikita Bhatnagar, Yeongmok Lee, Donghyuk Shin, Ka Young Chung, Sung Chul Lee, Beom-Gi Kim and Sangho Lee (2017). Modulation of ABA signaling by altering VxGΦL motif of PP2Cs in Oryza sativa. Mol. Plant 10(9):1190-1205. https://doi.org/10.1016/j.molp.2017.08.003. September 12, 2017.


[52] Ji-Hyung Lee, Su Myung Jung, Kyung-Min Yang, Eunjin Bae, Sung Gwe Ahn, Jin Seok Park, Dongyeob Seo, Minbeom Kim, Jihoon Ha, Jaewon Lee, Jun-Hyeong Kim, Jun Hwan Kim, Akira Ooshima, Jinah Park, Donghyuk Shin, Youn Sook Lee, Sangho Lee, Geert van Loo, Joon Jeong, Seong-Jin Kim and Seok Hee Park (2017). A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitination of Snail1. Nat. Cell Biol. 19(10):1260-1273. https://doi.org10.1038/ncb3609. October 1, 2017.


[51] Gyuhee Kim and Sangho Lee (2017). Crystallization and preliminary crystallographic analysis of IlvC, a ketol-acid reductoisomerase, from Streptococcus pneumoniae. Biodesign 5:40-43.


[50] Trung Thanh Thach, Yu-Jung Hong, Sangho Lee and Sung-Joon Lee (2017). Molecular determinants of the olfactory receptor Olfr544 activation by azelaic acid. Biochem. Biophys. Res. Commun. 485:241-248.


[49] ShinA Jang, Gyuhee Kim, Jihye Oh, Seungyeop Lee, Dongho Kim, Kook-Han Kim, Yong Ho Kim, Dong-Kwon Rhee and Sangho Lee (2017). Molecular characterization of a single-chain antibody variable fragment (scFv) specific for PspA from Streptococcus pneumoniae. Biochem. Biophys. Res. Commun. 482:141-146.


[48] Erik Norberg, Ana Lako, Pei-Hsuan Chen, Illana A Stanley, Feng Zhou, Scott B Ficarro, Bjoern Chapuy, Linfeng Chen, Scott Rodig, Donghyuk Shin, Dong Wook Choi, Sangho Lee, Margaret A Shipp, Jarrod A Marto and Nika N Danial (2017). Differential contribution of the mitochondrial translation pathway to the survival of diffuse large B-cell lymphoma subsets. Cell Death Differ. 24:251-262.




[47] Truc Kim, Jongkeun Choi, Sangho Lee, Kwon Joo Yeo, Hae-Kap Cheong and Kyeong Kyu Kim (2016). Structural studies on the extracellular domain of sensor histidine kinase YycG from Staphylococcus aureus and its functional implications. J. Mol. Biol. 428:3074-3089.


[46] Donghyuk Shin, Seungsu Han and Sangho Lee (2016). Structure determination of biological macromolecular complexes by small-angle X-ray scattering (SAXS) combined with validating tools. Biodesign 4:20-26.


[45] Trung Thanh Thach, Donghyuk Shin, Seungsu Han and Sangho Lee (2016). New conformations of linear polyubiquitin chains by crystallographic and solution scattering studies expand the conformational space of polyubiquitin. Acta Cryst. D72:524-535.




[44] Trung Thanh Thach, Namsoo Lee, Donghyuk Shin, Seungsu Han, Gyuhee Kim, Hongtae Kim, and Sangho Lee (2015) Molecular Determinants of Polyubiquitin Recognition by Continuous Ubiquitin-Binding Domains of Rad18. Biochemistry 54:2136-2148.


[43] Sang-Sang Park, Hyog-Young Kwon, Thao Dang-Hien Tran, Moo-Hyun Choi, Seung-Ha Jung, Sangho Lee, David E. Briles, and Dong-Kwon Rhee (2015). ClpL is a chaperone without auxiliary factors. FEBS J. 282:1352-1367.


[42] Youn Sook Lee, Jin Seok Park, Su Myung Jung, Sang-Doo Kim, Jun Hwan Kim, Jae Young Lee, Kyeong Cheon Jung, Mizuko Mamura, Sangho Lee, Seong-Jin Kim, Yoe-Sik Bae, and Seok Hee Park (2015). Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide. EMBO Mol. Med. 7:577-592.




[41] Shuo Ren, Yuanyuan Jiang, Hye Rim Yoon, Sun Woo Hong, Donghyuk Shin, Sangho Lee, Dong-ki Lee, Moonsoo M. Jin, Irene M. Min, and Soyoun Kim (2014) Label-free Detection of the Transcription Initiation Factor Assembly and Specific Inhibition by aptamers. Bull. Korean Chem. Soc. 35:1279.


[40] Donghyuk Shin, Gwanho Kim, Gyuhee Kim, Xu Zheng, Yang-Gyun Kim, and Sangho Lee (2014). Structural and biochemical characterizations of an intramolecular tandem coiled coil protein. Biochem. Biophys. Res. Commun. 455:339-46.


[39] Trung Thanh Thach, and Sangho Lee (2014). New crystal structures of adenylate kinase from Streptococcus pneumoniae D39 in two conformations. Acta Cryst. F70:1468-71.


[38] Doyoun Kim, Jeonghwan Hur, Kwangsoo Park, Sangsu Bae, Donghyuk Shin, Sung Chul Ha, Hye-Yeon Hwang, Sungchul Hohng, Joon-hwa Lee, Sangho Lee, Yang-Gyun Kim, and Kyeong Kyu Kim (2014). Distinct Z-DNA binding mode of a PKR-like protein kinase containing a Z-DNA binding domain (PKZ). Nucleic Acids Res. 42:5937-5948.


[37] Trung Thanh Thach, Truc Thanh Luong, Sangho Lee*, and Dong-Kwon Rhee* (2014). Adenylate kinase from Streptococcus pneumoniae is essential for growth through its catalytic activity. FEBS Open Bio 4:672-682. (* Corresponding authors)


[36] Seungsu Han, Donghyuk Shin, Hoon Choi, and Sangho Lee (2014). Molecular determinants of the interaction between Doa1 and Hse1 involved in endosomal sorting. Biochem. Biophys. Res. Commun. 446:352-357.




[35] Sun-Jick Kim, Jang-Won Ahn, Hee Kim, Hee-Jin Ha, Sang-Woo Lee, Hyun-Kuk Kim, Sanghoe Lee, Hyun-Seok Hong, Young Ho Kim and Cheol Yong Choi (2013). Two β-strands of RAGE participate in the recognition and transport of amyloid-β peptide across the blood brain barrier. Biochem. Biophys. Res. Commun. 439:252-257.


[34] Hye-Ji Choi, Ye-Jin Kim, Sangho Lee, and Young-Sung Kim (2013). A heterodimeric Fc-based bispecific antibody simultaneously targeting VEGFR-2 and Met exhibits potent antitumor activity. Mol. Cancer Ther. 12:2748-2759.


[33] Yoshikatsu Aikawa and Sangho Lee (2013). Role of Rabex-5 in the sorting of ubiquitinated cargo at an early stage in the endocytic pathway. Commun. Integ. Biol. 6:4, e24463.


[32] Hai Minh Ta, Sangsu Bae, Seungsu Han, Jihyuck Song, Tae Kyu Ahn, Sungchul Hohng, Sangho Lee and Kyeong Kyu Kim (2013). Structure-based elucidation of the regulatory mechanism for aminopeptidase activity. Acta Cryst. D69:1738-1747.




[31] Yoshikatsu Aikawa, Hideki Hirakawa, and Sangho Lee (2012). Spatiotemporal regulation of the ubiquitinated cargo-binding activity of Rabex-5 in the endocytic pathways. J. Biol. Chem. 287(48):40586-40597.


[30] Donghyuk Shin, Sei Young Lee, Seungsoo Han, Shuo Ren, Soyoun Kim, Yoshikatsu Aikawa, and Sangho Lee (2012). Differential polyubiquitin recognition by tandem ubiquitin binding domains of Rabex-5. Biochem. Biophys. Res. Commun. 423:757-782.


[29] Byeong-Gu Han, Kyung-Chae Jeong, Jea-Won Cho, Buyng-Cheon Jeong, Hyun Kyu Song, Jae Young Lee, Dong Hyuk Shin, Sangho Lee, and Byung Il Lee (2012). Crystal structure of Pyrococcus furiosus PF2050, a member of the DUF2666 protein family. FEBS Lett. 586:1384-1388.


[28] Thanh Trung Thach, JunGoo Jee, and Sangho Lee (2012). Effects of a phosphomimetic mutant of RAP80 on linear polyubiquitin binding probed by calorimetric analysis. Bull. Korean Chem. Soc. 33(4):1285-1289.


[27] Young-Hee Cho, Sangho Lee, and Sang-Dong Yoo (2012). EIN2 and EIN3 in Ethylene signaling. Annu. Plant Rev. 44:169-188. (Book chapter)


[26] Byeong-Gu Han, Kyoung Hoon Kim, Sang Jae Lee, Kyung-Chae Jeong, Jea-Won Cho, Kyung Hee Noh, Tae Woo Kim, Soon-Jong Kim, Hye-Jin Yoon, Se Won Suh, Sangho Lee, and Byung Il Lee (2012). Helical repeat structure of apoptosis inhibitor 5 reveals protein-protein interaction modules. J. Biol. Chem. 287(14):10727-10737.


[25] Hoon Choi, Seungsoo Han, Donghyuk Shin, and Sangho Lee (2012). Polyubiquitin recognition by AtSAP5, an A20-type zinc finger containing protein from Arabidopsis thaliana. Biochem. Biophys. Res. Commun. 419(2):436-440.


[24] Hyon-Seung Yi, Young Sil Eom, Ie Byung Park, Sangho Lee, Suntaek Hong, Harald Juppner, Michael Mannastadt, and Sihoon Lee (2012). Identification and characterization of C106R, a novel mutation in the DNA-binding domain of GCMB, in a family with autosomal dominant hypoparathyroidism. Clin. Endocrinol. 76(5):625-633.




[23] Dong-Wan Kim, Hyun Sung, Donghyuk Shin, Haihong Shen, Joohong Ahnn, Sun-Kyung Lee*, and Sangho Lee* (2011). Differential Physiogical Roles of ESCRT Complexes in Caenorhabditis elegans. Mol. Cells 31(6):585-592. (* Corresponding authors)


[22] Meenakshi Dwivedi, Hyun Sung, Haihong Shen, Byung-Jae Park*, and Sangho Lee* (2011). Disruption of Endocytic Pathway Regulatory Genes Activates Autophagy in C. elegans. Mol. Cells 31(5):477-481. (* Corresponding authors)


[21] Kyungmin Kim, Bulat I. Khayrutdinov, Chung-Kyung Lee, Hae-Kap Cheong, Sung Wook Kang, Hyejin Park, Sangho Lee, Yang-Gyun Kim, JunGoo Jee, Alexander Rich*, Kyeong Kyu Kim*, and Young Ho Jeon* (2011). Solution structure of the Z domain of human DNA-dependent activator of IFN-regulatory factors and its binding modes to B- and Z-DNAs. Proc. Natl. Acad. Sci. U.S.A. 108:6921-6926. (* Corresponding authors)




[20] Byeong-Gu Han, Kyeongsik Min, Byung Il Lee* and Sangho Lee* (2010). Refined structure of human NM23-H1 from a hexagonal crystal. Bull. Korean Chem. Soc. 31(5):1397-1399. (* Corresponding authors)


[19] Byeong-Gu Han, Jea-Won Choa, Young-Doo Cho, Soo-Youl Kim, Hye-Jin Yoon, Hyun Kyu Song, Hae-Kap Cheong, Young-Ho Jeon, Dong-ki Lee, Sangho Lee* and Byung Il Lee* (2010). Expression, purification and biochemical characterizations of the N-terminal regions of human TIG3 and HRASLS3 proteins. Protein Expr. Purif. 71(1):103-107. (* Corresponding authors)


[18] Doyoun Kim, Boi Hoa San, Sang Hyun Moh, Hyejin Park, Dong Young Kim, Sangho Lee* and Kyeong Kyu Kim* (2010). Structural basis for the substrate specificity of PepA from Streptococcus pneumoniae, a dodecameric tetrahedral protease. Biochem. Biophys. Res. Commun. 391(1):431-436. (* Corresponding authors)




[17] Hyun-Jung Cho, Sangho Lee and Hongtae Kim (2009). The linker connecting the tandem ubiquitin binding domains of RAP80 is criticial for lysine 63-linked polyubiquitin-dependent binding activity. BMB Rep. 42(11):764-768.


[16] Jae Yoon Shin, Jae Il Shin, Jun Seob Kim, Yoo Soo Yang, Yeon-Kyun Shin, Kyeong Kyu Kim, Sangho Lee and Dae-Hyuck Kweon (2009). Disulfide bond as a structural determinant of prion protein membrane insertion. Mol. Cells 27:673-680.


[15] Yoo-Soo Yang, Jae-Il Shin, Jae-Yoon Shin, Jung-Mi Oh, Sang Ho Lee, Joo-Sung Yang and Dae-Hyuk Kweon (2009). Prion protein does not interfere with SNARE complex formation and membrane fusion. Food Sci. Biotechnol. 18(3):782-787.


[14] Doyoun Kim, Sanjith Reddy, Dong Young Kim, Alexander Rich, Sangho Lee, Kyeong Kyu Kim and Yang-Gyun Kim (2009). Base extrusion is found at helical junctions between right- and left-handed forms of DNA and RNA. Nucleic Acids Res. 37(13):4353-4359.


[13] So Jung Park, Hee Jung Park, Sangho Lee and Yang-Gyun Kim (2009). Structural elements contributing to efficient -1 ribosomal frameshifting in BWYV pseudoknot. Bull. Korean Chem. Soc. 30, 509-912.


[12] Hee Jung Park, So Jung Park, Doo-Byoung Oh, Sangho Lee* and Yang-Gyun Kim* (2009). Increased -1 ribosomal frameshifting efficiency by yeast prion-like phenotype [PSI+]. FEBS Lett. 583, 665-669. (* Corresponding authors)




[11] Sangho Lee (2008). Crystal structure of the metal-bound superoxide dismutase from Pyrobaculum aerophilum and comparison with the metal-free form. Bull. Korean. Chem. Soc. 29, 2399-2402.



2002 - 2007

[10] Dong Van Quyen, Sung Chul Ha, Doyoun Kim, Sangho Lee, So-Jung Park, Kyeong Kyu Kim and Yang-Gyun Kim (2007). Binding surface in Zβ domain from human ZBP1 does not require conserved proline residues for Z-DNA binding and B-to-Z-DNA conversion activities. Bull. Korean Chem. Soc. 28, 2539-2542.


[9] Michael S. Kostelansky, Cayetana Schluter, Yuen Yi C. Tam, Sangho Lee, Rodolfo Ghirlando, Bridgette Beach, Elizabeth Conibear and James H. Hurley (2007). Molecular architecture and functional model of the complete yeast ESCRT-I heterotetramer. Cell 129, 485-498.


[8] Sangho Lee, Anjali Joshi, Kunio Nagashima, Eric O. Freed and James H. Hurley (2007). Structural basis for viral late-domain binding to Alix. Nat. Struct. Mol. Biol. 14, 194-199. (Selected for cover)


[7] James H. Hurley, Sangho Lee and Gali Prag (2006). Ubiquitin-binding domains. Biochem. J. 399, 361-372. (Review)


[6] Michael S. Kostelansky, Ji Sun*, Sangho Lee*, Jaewon Kim*, Rodolfo Ghirlando, Aitor Hierro, Scott D. Emr and James H. Hurley (2006). Structural and functional organization of the ESCRT-I trafficking complex. Cell 125, 113-126. (* Equal contribution)


[5] Sangho Lee, Yien Che Tsai, Rafael Mattera, William J. Smith, Michael S. Kostelansky, Allan M. Weissman, Juan S. Bonifacino and James H. Hurley (2006). Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5. Nat. Struct. Mol. Biol. 13, 264-271. (Selected as the “Article of The Month”)


[4] Gali Prag*, Sangho Lee*, Rafael Mattera, Cecilia N. Arighi, Bridgette M. Beach, Juan S. Bonifacino and James H. Hurley (2005). Structural mechanisms for ubiquitinated cargo recognition by the Golgi-localized, γ-ear-containing, ADP-ribosylation-factor-binding proteins. Proc. Natl. Acad. Sci. U.S.A. 102, 2334-2339. (* Equal contribution)


[3] Sangho Lee and David Eisenberg (2003). Seeded conversion of recombinant prion protein to a disulfide-bonded oligomer by a reduction-oxidation process. Nat. Struct. Biol. 10, 725-730.


[2] Sangho Lee, Michael R. Sawaya and David Eisenberg (2003). Structure of superoxide dismutase from Pyrobaculum aerophilum presents a challenging case in molecular replacement with multiple molecules, pseudo-symmetry and twinning. Acta Cryst. D59, 2191-2199.


[1] Ji-Heui Seo, Jong-Cheol Rah, Se Hoon Choi, Jae Kyung Shin, Kyeongsik Min, Hye-Sun Kim, Cheol Hyoung Park, Seonghan Kim, Eun-Mee Kim, Sang-Hyoung Lee, Sangho Lee, Se Won Suh and Yoo-Hun Suh (2002). α-Synuclein regulates neuronal survival via Bcl-2 family expression and PI3/Akt kinase pathway. FASEB J. 16, 1826-1828.